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As an organization dedicated to health, we will strive to ensure the health of people worldwide. |
| Management Philosophy |
We will contribute to promoting the health of all people worldwide. |
| We will provide safe, high-quality, and valuable products and services based on our daily
research and efforts. |
| We will conduct fair transactions, respect ethics, and comply with laws and regulations in order
to be a reliable enterprise. |
| We will perform sound management and develop as an enterprise contributing to health promotion. |
| We will effectively utilize resources and contribute to creating a healthy society
while assuring harmony with the local community and natural environment. |
| We will always endeavor to improve ourselves and perform our tasks to the best of our ability and
will assure full responsibility. |
| We will share the philosophy "health contribution" and our objectives and explore the future
with a spirit of creation and innovation. |
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The Japan Institute for the Control of Aging has conducted research into control of aging since its
foundation under the doctrine of contributing health promotion. As a result, the institute
succeeded in developing a DNA oxidative damage measuring kit, thus taking the lead for this field.
The institute now sells many products related to oxidative stress, and such products are utilized in
the fields of medicine, pharmacy, biochemistry, food sciences, etc. The institute also performs
assay services utilizing its unique technologies. Preventive medicine and anti-aging are receiving
increased attention with the advancement of aging society. In these areas, our Institute will
contribute to realizing a healthy, long-lived society by developing and supplying research products.
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| Company Name |
Japan Institute for the Control of Aging, Nikken SEIL Co., Ltd.
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| Representative |
Seiichi Ohi (president)
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| History |
1985 Founded the Japan Institute for the Control of Aging.
1986 Organized seminars on comfortable aging.
1990 Released oxidized DNA, 8-OHdG ELISA kit.
1995 Released oxidized lipid, anti 4-HNE
1998 Initiate the assay service as a registered sanitation inspection institute.
2000 Registered as a satellite center of the Trace Element Institute for UNESCO.
2003 Released oxidized lipid, HEL ELISA kit.
2008 Have patents for antioxidant assay kit PAO.
2012 Released oxidized protein Dityrosine ELISA kit.
2012 Have started radiation testing service.
2013 Received ISO/IEC 17025 certification (radioactivity testing).
2016 Have a new patent for antioxidant assay.
2017 Have a new patent for nitrosative stress assay.
2018 Opened a new office in Los Angeles for U.S. subsidiary Genox Corp.
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| Business of the institute |
Develop, manufacture and sell biomarkers used for measuring oxidative stress and antioxidants.
Assay services using biomarkers, such as urine and blood sampling tests and food antioxidant assays.
The Japan Institute for the Control of Aging is engaged in the kit reagent business and assay service business.
In the kit reagent business, our Institute develops, manufactures,
and sells research reagents used for measuring oxidative stress
markers. In addition, our Institute's monoclonal antibodies and
ELISA kits used for detecting products of oxidative damage
caused by reactive oxygen species are highly evaluated by
customers worldwide. The 8-OHdG Check (8-OHdG ELISA kit),
the main product of the Institute, was awarded the Ikeda Special
Prize of the Innovation Grand Prix in 1999 and a prize from the
Minister of Science and Technology Agency in 2000.
In the assay service business, we conduct sample testing on urine and blood and perform antioxidant
assays on foods based on the products we have developed and the analysis skills we have accumulated
over many years. Interest in preventive medicine, anti-aging, and functional foods has increased in recent
years. As a result, there have been growing number of requests from hospitals, universities, research
institutes, food manufacturers, and medicine manufacturers all over Japan to analyze oxidative stress
markers, aging-related hormones, and minerals.
 Download brochure (PDF: 1.7MB)
Download product catalog (PDF: 1.5MB)
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| Recent publications and presentations |
| [Poster] 17th Society for Free Radical Research International: SFRRI-2014 (Kyoto, 3/23-26, 2014) |
| [Poster] Society of Toxicology 52nd annual meeting (San Antonio, TX, U.S.A. 3/10-14, 2013) |
| [Poster] 35th Annual meeting of the Molecular Biology Society of Japan: MBSJ (Fukuoka, 12/11-14, 2012) |
| [Poster] 17th Annual meeting of Japan Society of Food Factors (Shizuoka, 11/10-11, 2012) |
| [Poster] 4th Slovenian Congress of Clinical Chemistry with International Participation and
20th International Symposium of Slovenian Association for Clinical Chemistry and Croatian Society of Medical Biochemists.
(Portoroz, Slovenia, September 28-29, 2012) |
| [Poster] 12th Annual meeting of Japan Society of Anti-Aging Medicine (Yokohama, 6/22-24, 2012) |
| [Poster] 65th Annual meeting of Society for Free Radical Research Japan: SFRR-J (Tokushima, 6/7-8, 2012) |
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K Sakai, S Kino, A Masuda, M Takeuchi, T Ochi,
J Osredkar, B Rejc, K Gersak, N Ramarathnam, Y Kato;
Determination of HEL (Hexanoyl-Lysine Adduct): A Novel Biomarker for Omega-6 PUFA Oxidation.
Lipid Hydroperoxide-Derived Modification of Biomolecules: Subcellular Biochemistry 77,p61-72(2014) |
| Barregard L, et. al.;
Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2'-deoxyguanosine.
Antioxid Redox Signal (2013) |
| XY Luo, T Takahara, J Hou, K Kawai, T Sugiyama, K Tsukada,
M Takemoto, M Takeuchi, L Zhong, XK Li;
Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model.
Biochem Biophys Res Commun 417,p287-293(2012) |
| Sun J, Sugiyama A, Masuda A, Ochi T, Takeuchi M.
Expressions of protein oxidation markers, dityrosine and advanced oxidation protein products in acetaminophen-induced
liver injury in rats. J Vet Med Sci. 73(9), p1185-1190 (2011) |
| Sugiyama A, Fujita Y, Kobayashi T, Ryu M, Suzuki Y, Masuda A, Ochi T, Takeuchi M
.Effect of protein malnutrition on the skin epidermis of hairless mice.
J Vet Med Sci. 73(6), p831-835 (2011) |
| Sugiyama A, Sun J, Nishinohara M, Fujita Y, Masuda A, Ochi T, Takeuchi M:
Expressions of lipid oxidation markers, N(epsiron)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity
in rats. J Vet Med Sci. 73(6), p821-826 (2011) |
| Kimoto Y, Sugiyama A, Nishinohara M, Asano A, Masuda A, Ochi T, Takeuchi M.
Expressions of protein oxidation markers, dityrosine and advanced oxidation protein products in Cisplatin-induced
nephrotoxicity in rats. J Vet Med Sci. 73(3), p403-407 (2011) |
| Sakai K, et.al. Analysis of antioxidant activities in vegetable oils and fat soluble
vitamins and biofactors by the PAO-SO method.
D Armstrong Ed., Adv Protocol Oxidative Stress II 594, p241-250 (2010) |
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| Contact |
TEL: +81-538-49-0125, FAX: +81-538-49-1267 (Supported language: Japanese/English)
Web site: http://www.jaica.com
E-mail: sales@jaica.com
NOTICE: We have been receiving huge number of spam mails and DDos attacks, and e-mails from some domains
may be rejected by our server. If your e-mails can't be sent correctly, please try to contact us by FAX.
Thank you very much for your understanding.
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| Address and how to reach JaICA |
Address: Haruoka 710-1, Fukuroi, Shizuoka, 437-0122 Japan
1) From Tokyo: Kakegawa sta. by Shinkansen(Kodama), and transfer to JR local train to reach Fukuroi sta.(total 2.5 hours).
2) From Nagoya/Osaka: Hamamatsu sta. by Shinkansen(Kodama), and transfer to JR local train (total 1.5 / 3 hours).
About 20 minutes drive by taxi from Fukuroi sta. of JR local train.
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| About link to JaICA web site/citation/exemption |
Link to our web site (http://www.jaica.com) will be allowed, but please avoid direct link to each product's page.
Citation will be allowed if the resource is written clealy as "JaICA" or "Japan Institute for the Control of Aging".
If you are planning to use pictures, figuares or sentences presented at our we site, written permission will be needed.
We are making efforts to prevent errors or mistakes on preparing web site documents, instruction manuals and products.
But even if some damage would causedby such faults, we will be exempt from responsibility.
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